Optimization path and implementation effectiveness of infection prevention and control interventions in a children’s hospital: a quantitative assessment

Objective This study aims to perform innovative quantitative assessments in managing healthcare-associated infections (HAIs) to pave the way for effective methods and pathways toward precise infection prevention and control (IPC). Methods A total of 61 diagnosis and treatment departments of a tertiary grade A children’s hospital were included in this study. By establishing a quantitative assessment form, we determined the database of IPC assessment indicators and implemented basic IPC quantitative assessment practices. The pre-practice stage (January 2017-December 2020) was set as the control group, and the practice stage (January 2021-December 2024) was set as the experimental group. A comparison of quality control indicators related to HAIs was conducted between the two groups, along with the observation of trends in IPC compliance rates at the hospital level and in key departments following implementation. Results The incidence rate of HAIs and the detection rate of multidrug-resistant organism infections in the experimental group were both lower than those in the control group, with p -values of