A pathologically diagnosed multinodular and vacuolating neuronal tumor without typical multiple nodules: a case report

Frontiers in Radiology 2026 Open access

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Authors: Ryota Kitano, Hiroaki Nagashima, Tomoaki Harada, Kazuhiro Tanaka, Keiichiro Uehara, Masamitsu Nishihara, Takashi Sasayama
DOI: 10.3389/fradi.2026.1718759
Cited by: 0
References: 24

Abstract

Multinodular and vacuolating neuronal tumors (MVNT) are glioneuronal and neuronal tumors classified as grade 1 in the 2021 World Health Organization classification of central nervous system tumors. These tumors are characterized by multiple nodules located between the deep cortex and subcortical white matter. Typically, patients are diagnosed radiologically and do not require treatment. This report describes a rare case of pathologically confirmed MVNT with radiological findings similar to those of low-grade glioma. Moreover, we highlight radiological features useful for differentiating MVNT from low-grade glioma.

Fields of Study & Subjects

Glioma Diagnosis and Treatment Tuberous Sclerosis Complex Research Meningioma and schwannoma management

Publication details

Journal / source
Frontiers in Radiology
Volume
6
Pages
1718759–1718759
Publication date
30 January 2026
Language
EN