A time-updated scoring system derived from a nomogram to predict 3-month mortality in maintenance hemodialysis patients

Objective: This study aimed to develop and validate a novel risk score for death within the next 3 months in patients with maintenance hemodialysis (MHD). Methods: All the data were derived in the Wuhan Hemodialysis Quality Control Center and were divided into the training set (2019-2021, n = 19,735) and the validation set (2022-2023, n = 15,265). The primary outcome was the all-cause mortality within 3 months after regular monthly laboratory tests. The predictive model was displayed as a nomogram and modified into a novel scoring system based on the coefficients of multivariable logistic regression. Results: There were 1684 (8.5%) patients and 1670 (10.9%) patients who died in the development and validation set, respectively. The final novel score system was calculated based on the five predictors: age ≥60 years (2 points), dialysis duration