Pediatric-adult split liver transplantation: an ethical imperative and systems-based roadmap for global expansion

Frontiers in Transplantation 2026 Open access

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Authors: Tran Cong Duy Long, Huynh Tran Bao Chau, Dat Tien Le, Thi Tran Nguyen Minh, Bùi Công Minh, Anh Le Thien Diep, Hoang Bao Tran Van, Truc Thi Thu Huynh, Nguyen Tien Huy
DOI: 10.3389/frtra.2025.1709770
Cited by: 1
References: 34

Abstract

This paradox emphasizes the urgent need to re-engineer transplant systems around pediatric-adult split liver transplantation (SLT). Despite being as effective as whole-liver transplants, SLT remains underutilized due to logistical and policy barriers. We believe that expanding SLT is not only clinically acceptable but a just and effective moral necessity. We propose a five-point action plan, including centralized splitting hubs, NMP-enabled transport, and global pilot programs, to transform SLT from an exception into standard practice.

Fields of Study & Subjects

Organ Transplantation Techniques and Outcomes Liver Disease and Transplantation Organ Donation and Transplantation

Publication details

Journal / source
Frontiers in Transplantation
Publisher
Frontiers Media SA
Volume
4
Pages
1709770–1709770
Publication date
23 January 2026
Language
EN