The Role And Relationship of Betatrophin With Some Biochemical Variables In Patients With Type 2 Diabetes

The study included estimating the level of betatrophin in the serum of patients with T2DM and its relationship with some clinical parameters in (60)sample as patients and(40)sample as control group . The results showed a significant increase in the concentration of betatrophin in patients, where it was (624.84±101.17pg/ml) compared to the healthy group, where it was (507.96±91.74pg/ml) and that the concentration of betatrophin increased with increasing age , body mass index (BMI) and was higher in females than males. the results also showed a significant increase in insulin resistance, Random glucose, fasting glucose, HbA1c, urea, creatinine, cholesterol, triglycerides, LDL-C,VLDL-C, atherogeneic index, liver enzymes AST, ALT, ALP and a significant decrease in HDL-C while there was non significant increase in insulin , in patients compared with control group, the results also showed there was a significant positive correlation between betatrophin and insulin,Random glucose, fasting glucose, HbA1c, TG, VLDL-C, liver enzymes ALT and AST,