Mitochondrial Stress in Helicobacter pylori Infection and Associated Malignancies: A Review

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Authors: Viola Varga, András Gelley, Éva Margittai, Buket Bagci, Edina A. Wappler-Guzzetta, Ibolya Czegle
Cited by: 4
References: 176

Abstract

Helicobacter pylori (H. pylori) infection is one of the most common bacterial infections worldwide. Its role in infection-associated cancers, such as gastric cancer and mucosa-associated lymphoid tissue (MALT) lymphoma is well known. However, mitochondrial alterations in these malignancies are less documented. Mitochondria are key organelles, maintaining cellular homeostasis under normal and pathological conditions. They regulate complex cellular processes and play a key role in carcinogenesis and cancer progression in H. pylori-associated malignancies. This review summarizes the role of mitochondrial stress in H. pylori infection, gastric cancer, and MALT lymphoma.

Fields of Study & Subjects

Helicobacter pylori-related gastroenterology studies Protein Tyrosine Phosphatases Cancer Stress Anesthesia and Immune Response

Publication details

Journal / source
Antioxidants
Publisher
MDPI AG
Volume
15
Issue
3
Pages
285–285
Publication date
25 February 2026
Language
EN