Bioactive Rocket (Eruca vesicaria subsp. sativa (Mill.) Hegi) Sprout Extracts: LC-MS Profiling and Skin-Protective Antioxidant and Enzyme Inhibitory Activities

Applied Sciences 2026 Open access

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Authors: Dorota Kasprzak, Katarzyna Wojciechowska, Aleksandra Nurzyńska, Sebastian Granica, Grażyna Ginalska, Ewa Poleszak, Katarzyna Dos Santos Szewczyk
DOI: 10.3390/app16147330
Cited by: 1
References: 45

Abstract

Eruca vesicaria subsp. sativa (rocket) sprouts are a rich source of bioactive compounds used in cosmetics. Phytochemical profiling (LC-PDA-MS/MS) of 5-day-old sprouts identified 26 metabolites, mainly glucosinolates (e.g., glucoraphanin and glucoerucin) and flavonol glycosides of quercetin and kaempferol. The extracts exhibited strong antioxidant activity in DPPH•, ABTS•+, and ferric-reducing assays and moderate, dose-dependent inhibition of skin-degrading enzymes: tyrosinase, elastase, and collagenase, suggesting anti-wrinkle and skin-brightening effects. Cytotoxicity assays on human BJ skin fibroblasts demonstrated that the rocket sprout extracts were non-cytotoxic at concentrations up to 125 µg/mL, with low-dose treatments enhancing the cell viability. Hemocompatibility tests confirmed safety, with

Fields of Study & Subjects

Genomics phytochemicals and oxidative stress Phytochemicals and Antioxidant Activities Silymarin and Mushroom Poisoning

Publication details

Journal / source
Applied Sciences
Publisher
MDPI AG
Volume
16
Issue
14
Pages
7330–7330
Publication date
22 July 2026
Language
EN