Volumetric Modulated Arc Therapy Versus Dynamic Conformal Arc Therapy for Single Isocenter Stereotactic Radiotherapy of Multiple Brain Metastases

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Authors: Theodoros Stroubinis, Maria Giannopoulou, Despoina Stasinou, Michalis Psarras, Anna G. Zygogianni, Maria Protopapa, Vassilis Kouloulias, Kalliopi Platoni
Cited by: 0
References: 34

Abstract

INTRODUCTION: Stereotactic radiosurgery is a highly precise radiotherapy technique widely used for the management of brain metastases. While VMAT enables highly conformal dose distributions, it is often associated with increased plan complexity and longer delivery times. Optimized dynamic conformal arc therapy (OptDCA) represents a less complex alternative that may achieve comparable dosimetric performance. In this retrospective study, dosimetric quality, deliverability, and plan complexity of VMAT and OptDCA were compared for single-isocenter SRS of multiple brain metastases. MATERIALS AND METHODS: Thirty patients previously treated with VMAT were randomly selected and replanned using OptDCA with identical beam arrangements. Plan quality was evaluated using the Paddick conformity index, gradient index, target coverage, MUs, and brain V12Gy and V20Gy. Deliverability was assessed using gamma passing rates, and plan complexity was quantified using multiple complexity metrics. RESULTS: VMAT achieved a slightly higher CI (0.72 vs. 0.71) but required a higher number of MUs (5376 vs. 4820), while no significant differences were observed in GI or target coverage. OptDCA demonstrated significantly higher GPR (median 96.95% vs. 91.1%) and consistently lower plan complexity. Significant correlations were observed between GPR and several complexity metrics for both techniques. CONCLUSION: Overall, OptDCA provides comparable plan quality to VMAT, while offering improved deliverability and reduced complexity, making it a viable alternative technique.

Fields of Study & Subjects

Advanced Radiotherapy Techniques Brain Metastases and Treatment Radiation Therapy and Dosimetry

Publication details

Journal / source
Bioengineering
Volume
13
Issue
2
Pages
207–207
Publication date
12 February 2026
Language
EN