Lipid Dependence of CYP3A4 Activity in Nanodiscs

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Authors: Ilia G. Denisov, Yelena V. Grinkova, Stephen G. Sligar
Cited by: 1
References: 59

Abstract

CYP3A4 is the main xenobiotic metabolizing enzyme in the human body, as it is in volved in metabolism of ~30% of drugs on the market as well as of many other compounds, from small molecules such as ethanol to large drugs such as erythromycin and cyclosporine [...].

Fields of Study & Subjects

Pharmacogenetics and Drug Metabolism Cancer Research and Treatment Animal testing and alternatives

Publication details

Journal / source
Biology
Publisher
MDPI AG
Volume
15
Issue
2
Pages
156–156
Publication date
15 January 2026
Language
EN