Whole-Genome Identification and Investigation of DNA Methylation Sites in Nosema ceranae
Abstract
DNA methylation is a key epigenetic modification involved in various biological processes. However, its role in Nosema ceranae remains poorly understood. In this study, we employed Oxford Nanopore Technology sequencing to identify whole-genome DNA methylation patterns in N. ceranae. A total of 140,711 CpG sites, 170,035 CHG sites, and 1,053,635 CHH sites were detected. Methylation was also observed at varying levels in repetitive genomic regions and different gene regions. Furthermore, three 5mC motifs were identified. These findings provide a foundation for investigation the epigenetic regulatory roles and mechanisms of DNA methylation in N. ceranae.
Fields of Study & Subjects
Insect symbiosis and bacterial influences
Epigenetics and DNA Methylation
Genomics and Phylogenetic Studies
Publication details
- Journal / source
- Biology
- Publisher
- MDPI AG
- Volume
- 15
- Issue
- 4
- Pages
- 299–299
- Publication date
- 8 February 2026
- Language
- EN