External Validation and Clinical Impact of the Barcelona Predictive Models for Detecting Significant Prostate Cancer in Prostate Biopsies in an Ibero-American Population

Cancers 2026 Open access

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Authors: Nahuel Paesano, Juan Camean, Maximiliano Ringa, Maximiliano López-Silva, Guido Koren, Tomás Eduardo Olmedo, Joaquín Ignacio Gurovich, Edgar Iván Bravo-Castro, Violeta Catalá, Pablo Contreras, Juan Justo-Quintas, José María Pérez-Ruiz
+6 more Silvia García‐Barreras, Berta Miró, Lucas Regis, Olga Méndez, Enrique Trilla, Juan Morote
DOI: 10.3390/cancers18111810
Cited by: 1
References: 29

Abstract

Objectives: To externally validate the Barcelona Predictive Models (BCN-PM 1 and 2) for detecting csPCa in an Ibero-American population. BCN-PM 1 was designed to reduce magnetic resonance imaging (MRI) use, whereas BCN-PM 2 aims to decrease unnecessary prostate biopsies. Methods: This prospective, multicenter study included 661 men with suspected PCa recruited in 2025 across three Ibero-American centers. All participants underwent MRI followed by targeted biopsies of lesions with the Prostate Imaging–Reporting and Data System (PI-RADS) ≥ 3, along with systematic biopsy. When PI-RADS lesions were

Fields of Study & Subjects

Prostate Cancer Diagnosis and Treatment Urinary Bladder and Prostate Research Prostate Cancer Treatment and Research

Publication details

Journal / source
Cancers
Publisher
MDPI AG
Volume
18
Issue
11
Pages
1810–1810
Publication date
1 June 2026
Language
EN