Neurodevelopment at Two Years in Preterm Infants: Corrected Versus Chronological Age

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Authors: Barbara Caravale, Valentina Focaroli, Elvira Caramuscio, Cristina Zitarelli, Francesco Pisani, Corinna Gasparini, Paola Ottaviano, Antonella Castronovo, Marzia Paoletti, Daniela Regoli, Lucia Dito, Gianluca Terrin
+1 more Rosa Ferri
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References: 37

Abstract

Background: Preterm birth is a significant risk factor for neurodevelopmental delays, but the appropriate use and timing of age correction for developmental assessment remain debated. Objective: This study investigated psychomotor development in preterm children at two years of age, with the aim of clarifying whether age correction remains necessary at this stage, particularly across different gestational age groups. Methods: A total of 161 preterm infants were assessed at a mean chronological age of 25.4 months (mean corrected age: 23.3 months) and compared with two control groups of typically developing children matched for gender and either corrected age (Control–Corr, N = 88) or chronological age (Control–Chron, N = 87). The preterm group was further stratified by gestational age: extremely preterm (

Fields of Study & Subjects

Infant Development and Preterm Care Neonatal and fetal brain pathology Preterm Birth and Chorioamnionitis

Publication details

Journal / source
Children
Volume
13
Issue
2
Pages
219–219
Publication date
4 February 2026
Language
EN