Registered Prevalence and Regional Characteristics of Congenital Anomalies in the Turkistan Region

BACKGROUND: Congenital disorders (CDs) are a major contributor to perinatal morbidity and mortality, and their prevalence may vary by region. This study aimed to assess the epidemiological characteristics and regional features of congenital anomalies (CAs) in the Turkistan Region and to evaluate temporal trends and forecast near-term dynamics. METHODS: A retrospective analysis was conducted using data from regional perinatal centers and medical institutions in the Turkistan Region for 2020-2024. The total number of registered pregnancies and diagnosed CA cases were summarized annually. RESULTS: From 2020 to 2024, 53,169 pregnancies were registered and 848 cases of CAs were identified, yielding an overall prevalence of 1.6%. The registered prevalence of CAs increased from 0.8% in 2020 to 2.4% in 2024. This temporal increase coincided with the expansion of prenatal screening and diagnostic services in the region during the study period. CONCLUSIONS: The findings demonstrate an increase in the registered prevalence of CAs in the Turkistan Region over the study period. The observed trend may reflect both changes in case detection and registration practices, as well as possible epidemiological influences, highlighting the importance of continued surveillance and prenatal diagnostic services.