Quaternary Phosphonium Salts Outperformed Vemurafenib (PLX) and Etoposide Against BRAFV600D,V600E PLX-Resistant Melanoma and MDR Neuroblastoma, Exhibiting No/Low Toxicity on 3T3/HaCaT Cells

International Journal of Molecular Sciences 2026 Open access

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Authors: Silvana Alfei, Maria Grazia Signorello, Sara Tirendi, Elaheh Khaledizadeh, Paolo Giordani, Caterina Reggio, Barbara Marengo, Cinzia Domenicotti
DOI: 10.3390/ijms27073170
Cited by: 1
References: 81

Abstract

Late-stage metastatic cutaneous melanoma (MCM) and neuroblastoma (NB) are the most aggressive skin and childhood cancers with survival rates of

Fields of Study & Subjects

Melanoma and MAPK Pathways Synthesis and biological activity Beetle Biology and Toxicology Studies

Publication details

Journal / source
International Journal of Molecular Sciences
Publisher
MDPI AG
Volume
27
Issue
7
Pages
3170–3170
Publication date
31 March 2026
Language
EN