Therapeutic Innovations for Monkeypox Inhibition

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Authors: Nayan De, Jhuma Bhadra, Md Sorique Aziz Momin, Kamala Mitra, Debmalya Bhunia, Achinta Sannigrahi
Cited by: 1
References: 90

Abstract

This review investigates biomaterial-based strategies for improved treatment of MPXV. We focus on emerging synthetic biomedical approaches to combating the virus. These include peptide nucleic acids, CRISPR-based systems, and small-molecule therapeutics. These methods work by targeting and blocking viral proteins and enzymes. Such synthetic platforms may help reduce viral transmission and minimize side effects. They also offer potential solutions to challenges such as viral resistance in humans. In addition, biomaterials contribute to the development of more stable and effective vaccines. Combining these biomaterials with mRNA technology provides a promising framework for future vaccine development. Overall, this review underscores biomaterial-driven antiviral systems as a major frontier in translational medicine with profound implications for global health and pandemic awareness.

Fields of Study & Subjects

Poxvirus research and outbreaks Virus-based gene therapy research Viral Infections and Outbreaks Research

Publication details

Journal / source
International Journal of Molecular Sciences
Publisher
MDPI AG
Volume
27
Issue
10
Pages
4307–4307
Publication date
12 May 2026
Language
EN