High-Risk Coronary Plaques and Carotid Duplex Findings in Asymptomatic Patients Undergoing Primary Prevention Assessment

Journal of Cardiovascular Development and Disease 2026 Open access

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Authors: Lucio Addeo, Pasquale Guarini, Carlo Tedeschi, Antonio Rapacciuolo, Salvatore Severino, Mario De Michele, Milena Sidiropulos, Mattia Silvestre, Carlo Liguori, Luigi Cocchiara, Stefano Nardi, Luigi Argenziano
+5 more Vittoria Marino, Pasquale Campana, Roberto F.E. Pedretti, Maurizio Bussotti, Laura Adelaide Dalla Vecchia
DOI: 10.3390/jcdd13020088
Cited by: 0
References: 18

Abstract

Subclinical coronary atherosclerosis is common but its biological aggressiveness and interplay with extracoronary disease in asymptomatic individuals remain unclear. We evaluated the prevalence of high-risk coronary plaques (HRPs) and their relationship with mild carotid atherosclerosis and coronary calcium in a cardiovascular (CV) high-risk cohort in primary prevention. This retrospective multicenter study enrolled 269 asymptomatic adults with multiple CV risk factors who underwent Coronary Computed Tomography Angiography (CCTA) after prior carotid duplex ultrasound (CDUS). Coronary artery disease (CAD) was graded as absent, non-obstructive (

Fields of Study & Subjects

Cardiac Imaging and Diagnostics Cerebrovascular and Carotid Artery Diseases Health Promotion and Cardiovascular Prevention

Publication details

Journal / source
Journal of Cardiovascular Development and Disease
Volume
13
Issue
2
Pages
88–88
Publication date
11 February 2026
Language
EN