Asymptomatic Aortic Regurgitation: Evolving Imaging Markers and Contemporary Intervention Strategies

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Authors: Chieh-Mei Tsai, Kuan-Yu Lai, Yu‐Jang Su, Chi‐Han Wu, Casper H. H. Tsai, Shivam Singh, Li‐Tan Yang
Cited by: 1
References: 105

Abstract

Asymptomatic aortic regurgitation (AR) has traditionally been managed conservatively until symptom onset or overt left ventricular systolic dysfunction. However, adverse myocardial remodeling-detected by myocardial strain, volumetric cardiac magnetic resonance, and fibrosis imaging-often precedes current guideline thresholds for interventions and may be irreversible. Advances in multimodal imaging now enable earlier risk stratification beyond conventional metrics. In parallel, intervention strategies are evolving, including valve repair, valve-sparing root replacement, Ross procedure, and transcatheter aortic valve replacement in selected high-risk patients. This narrative review summarizes contemporary advances in imaging and intervention for asymptomatic AR, while critically appraising current evidentiary and technical limitations that constrain earlier intervention. The review is based on a narrative synthesis of the contemporary literature, drawing from recent clinical studies, imaging advances, and guideline documents rather than a systematic evidence search.

Fields of Study & Subjects

Cardiac Valve Diseases and Treatments Aortic Disease and Treatment Approaches Infective Endocarditis Diagnosis and Management

Publication details

Journal / source
Journal of Clinical Medicine
Publisher
MDPI AG
Volume
15
Issue
1
Pages
339–339
Publication date
2 January 2026
Language
EN