CLR (CRP to Lymphocytes) Score for Differentiating Simple and Complicated Appendicitis in Pediatric Patients
Abstract
Background: Acute appendicitis, a frequent pediatric surgical emergency, requires distinguishing simple from complicated cases for treatment decisions. Current tools, such as clinical scores and ultrasound, are sometimes ineffective. This study evaluates the biomarkers: neutrophils to lymphocytes ratio (NLR), monocytes to lymphocytes ratio (MLR), platelet-to-lymphocyte ratio (PLR), neutrophils to monocytes ratio (NMR), neutrophils to platelet ratio (NPR), pan-immune-inflammation value (PIV) ratio, and C-Reactive Protein (CRP) to lymphocytes ratio (CLR) for differentiation between simple and complicated appendicitis. Methods: A retrospective study of 878 pediatric patients (
Fields of Study & Subjects
Appendicitis Diagnosis and Management
Inflammatory Biomarkers in Disease Prognosis
Diagnosis and treatment of tuberculosis
Publication details
- Journal / source
- Journal of Clinical Medicine
- Publisher
- MDPI AG
- Volume
- 15
- Issue
- 1
- Pages
- 393–393
- Publication date
- 5 January 2026
- Language
- EN