Intralesional Corticosteroid Injections in the Treatment of Oral Lichen Planus—A Narrative Review
Abstract
Background: Oral lichen planus (OLP) is a chronic inflammatory autoimmune disease. Certain clinical forms of the disease may cause significant discomfort and negatively impact patients’ quality of life. The first-line treatment is topical corticosteroids. The purpose of this narrative review is to evaluate the influence of corticosteroid injections in the treatment of OLP. Methods: A search of the literature was conducted in October 2025 using the following databases: PubMed, Web of Science, Scopus, and Cochrane. Results: Fifteen studies were evaluated. Injections with triamcinolone acetonide at a concentration of 10–40 mg/mL at weekly intervals demonstrated efficacy in reducing pain and healing OLP lesions in these studies. They showed minor adverse effects. Conclusions: Noting the limitations of this narrative review, intralesional corticosteroid injections are an effective and safe method of treating OLP. They should be considered in patients with symptomatic OLP.
Fields of Study & Subjects
Oral Health Pathology and Treatment
Salivary Gland Disorders and Functions
Genital Health and Disease
Publication details
- Journal / source
- Journal of Clinical Medicine
- Publisher
- MDPI AG
- Volume
- 15
- Issue
- 2
- Pages
- 561–561
- Publication date
- 9 January 2026
- Language
- EN