Intralesional Corticosteroid Injections in the Treatment of Oral Lichen Planus—A Narrative Review

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Authors: Weronika Miazga-Rychlik, Emilia Milczarek, Jan Kowalski, Aniela Brodzikowska, Bartłomiej Górski
Cited by: 2
References: 38

Abstract

Background: Oral lichen planus (OLP) is a chronic inflammatory autoimmune disease. Certain clinical forms of the disease may cause significant discomfort and negatively impact patients’ quality of life. The first-line treatment is topical corticosteroids. The purpose of this narrative review is to evaluate the influence of corticosteroid injections in the treatment of OLP. Methods: A search of the literature was conducted in October 2025 using the following databases: PubMed, Web of Science, Scopus, and Cochrane. Results: Fifteen studies were evaluated. Injections with triamcinolone acetonide at a concentration of 10–40 mg/mL at weekly intervals demonstrated efficacy in reducing pain and healing OLP lesions in these studies. They showed minor adverse effects. Conclusions: Noting the limitations of this narrative review, intralesional corticosteroid injections are an effective and safe method of treating OLP. They should be considered in patients with symptomatic OLP.

Fields of Study & Subjects

Oral Health Pathology and Treatment Salivary Gland Disorders and Functions Genital Health and Disease

Publication details

Journal / source
Journal of Clinical Medicine
Publisher
MDPI AG
Volume
15
Issue
2
Pages
561–561
Publication date
9 January 2026
Language
EN