Association of Proton Pump Inhibitor Use with Cancer in Patients Undergoing Maintenance Hemodialysis: A Population-Based Cohort Study

Journal of Clinical Medicine 2026 Open access

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Authors: Seok Hui Kang, So Young Park, Yu Jeong Lim, Bo Yeon Kim, Ji Young Choi, Jun-Young Do
DOI: 10.3390/jcm15030920
Cited by: 0
References: 24

Abstract

Background: Despite widespread proton pump inhibitor (PPI) use in hemodialysis (HD), evidence on cancer risk in high-risk populations remains scarce. We investigated the association between PPI use and incident cancer in a population-based cohort of patients receiving HD. Methods: We used data from the 4th–7th HD quality assessments from South Korea and data linked to claims and death. We classified patients by PPI prescription over 1 year, including No-Prescription (no PPI during the year, n = 37,934); Short (PPI for

Fields of Study & Subjects

Inflammatory mediators and NSAID effects Helicobacter pylori-related gastroenterology studies Gastroesophageal reflux and treatments

Publication details

Journal / source
Journal of Clinical Medicine
Volume
15
Issue
3
Pages
920–920
Publication date
23 January 2026
Language
EN