Premenstrual Syndrome and Nutritional Factors: A Narrative Review of Current Evidence and Clinical Implications

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Authors: Francesco Giuseppe Martire, Eugenia Costantini, Ilaria Ianes, Claudia d’Abate, Maria De Bonis, Emilio Piccione, A. Andréoli
Cited by: 1
References: 108

Abstract

Premenstrual syndrome is a common hormone-related condition marked by recurrent physical and affective symptoms that can substantially impair daily functioning. While cyclical ovarian hormone fluctuations are physiological, clinically relevant symptoms occur only in a subset of women, indicating the contribution of individual vulnerability and modifiable environmental factors. In this context, growing attention has been directed toward the role of nutrition. This narrative review synthesizes and critically discusses current evidence on the relationship between dietary factors and premenstrual syndrome, with emphasis on both primary prevention and symptom modulation. Available observational and interventional data suggest that dietary patterns characterized by high intake of ultra-processed foods, refined carbohydrates, and saturated fats are more frequently associated with increased symptom severity, whereas healthier dietary patterns may be linked to a lower symptom burden. Certain micronutrients-including calcium, vitamin D, zinc, iron, and omega-3 fatty acids-have demonstrated potential benefits, although findings remain heterogeneous and methodologically limited. Overall, nutrition emerges as a plausible complementary strategy in premenstrual syndrome management; however, well-designed prospective studies are needed to support robust, evidence-based dietary recommendations.

Fields of Study & Subjects

Menstrual Health and Disorders Biochemical effects in animals Menopause: Health Impacts and Treatments

Publication details

Journal / source
Journal of Clinical Medicine
Publisher
MDPI AG
Volume
15
Issue
3
Pages
1124–1124
Publication date
31 January 2026
Language
EN