Substance Use Disorders and the Psychosis Spectrum: Assessment, Clinical Challenges and Management

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Authors: Thomas J. Paparrigopoulos, E. Mellos, Charidimos Tzagarakis
Cited by: 1
References: 102

Abstract

The intricate relationship between substance-induced psychotic disorders and primary disorders of the psychosis spectrum requires practitioners to meticulously evaluate patient history, substance use patterns, and clinical symptomatology. Also, the dual diagnosis of SUDs and psychotic disorders exacerbates treatment challenges, often leading to the need to coordinate differing treatment modalities and fragmented care. A nuanced understanding of the interplay between SUDs and the psychosis spectrum is crucial for effective assessment and comprehensive management strategies. In this review, the unique challenges presented by this complex clinical population are examined, and management strategies are explored.

Fields of Study & Subjects

Schizophrenia research and treatment Substance Abuse Treatment and Outcomes Neurotransmitter Receptor Influence on Behavior

Publication details

Journal / source
Journal of Clinical Medicine
Publisher
MDPI AG
Volume
15
Issue
4
Pages
1562–1562
Publication date
16 February 2026
Language
EN