Adherence to CPAP in Randomized Controlled Trials in Obstructive Sleep Apnoea—A Meta-Analysis and Investigation of Predictors
Abstract
Background: Continuous positive airway pressure (CPAP) is the most effective treatment for obstructive sleep apnoea (OSA). However, CPAP adherence in randomized controlled trials (RCTs) is frequently inadequate, potentially leading to an underestimation of the therapy’s true effect on relevant outcomes. The aim was to identify patient and study characteristics that predict adherence to CPAP therapy in RCTs. Methods: PubMed and the existing meta-analyses were searched (1984 to 31 December 2024). A study-level meta-analysis of RCTs comparing CPAP with inactive control in patients with OSA was conducted. Meta-regressions and subgroup analyses (
Fields of Study & Subjects
Obstructive Sleep Apnea Research
Sleep and related disorders
Chronic Obstructive Pulmonary Disease (COPD) Research
Publication details
- Journal / source
- Journal of Clinical Medicine
- Publisher
- MDPI AG
- Volume
- 15
- Issue
- 9
- Pages
- 3264–3264
- Publication date
- 24 April 2026
- Language
- EN