Artificial Intelligence in the Detection of Papilledema: A Systematic Review

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Authors: Ovidiu Samoilă, Vasiliki Antonoupoulou, Lăcrămioara Samoilă
Cited by: 1
References: 38

Abstract

Background/Objectives: This review explores the role of artificial intelligence (AI), particularly with deep learning and machine learning, in the detection and classification of papilledema using retinal fundus imaging. Methods: The study synthesizes historical, technical, and clinical insights, comparing AI-based diagnostic accuracy with conventional methods. Results: Our findings demonstrate that AI systems, especially convolutional neural networks (CNNs), offer sensitivity and specificity comparable to, or even surpassing, expert-level fundoscopy. Conclusions: These results suggest significant implications for early diagnosis, triage, and telemedicine integration in ophthalmic care.

Fields of Study & Subjects

Retinal Imaging and Analysis Artificial Intelligence in Healthcare and Education Ophthalmology and Visual Health Research

Publication details

Journal / source
Journal of Clinical Medicine
Publisher
MDPI AG
Volume
15
Issue
13
Pages
4878–4878
Publication date
23 June 2026
Language
EN