Biomaterials for Improving Skin Penetration in Treatment of Skin Cancer

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Authors: Davide Secci, Andrew J. Urquhart, Vasileios Bekiaris, Katrine Qvortrup
Cited by: 5
References: 134

Abstract

Skin cancer is among the most common malignancies worldwide, posing a significant societal burden due to its increasing incidence and its limited responsiveness to conventional topical therapies. Treatment is challenged by the presence of the skin barrier which restricts drug penetration. This review discusses the structural and physiological challenges of topical delivery and summarizes efforts to develop functional biomaterials to enhance skin drug penetration. Important aspects to consider when developing formulation strategies, such as drug properties and release mechanisms, are discussed alongside current limitations and future perspectives.

Fields of Study & Subjects

Advancements in Transdermal Drug Delivery Advanced Drug Delivery Systems Wound Healing and Treatments

Publication details

Journal / source
Journal of Functional Biomaterials
Publisher
MDPI AG
Volume
17
Issue
1
Pages
39–39
Publication date
15 January 2026
Language
EN