The Role of Transcranial Magnetic Stimulation for the Treatment of Alzheimer’s Disease: A Narrative Review

Life 2026 Open access

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Authors: Vasileios T. Papaliagkas, Kallirhoe Kalinderi, Maria Moschou, Marianthi Arnaoutoglou, Effrosyni Koutsouraki, Vasilios Κ. Kimiskidis
DOI: 10.3390/life16030397
Cited by: 0
References: 41

Abstract

Alzheimer's disease (AD) is the most common neurodegenerative disease that accounts for 60-80% of all dementia cases and affects millions of people worldwide. At present, standard drug therapies provide only limited symptomatic relief. Therefore, the exploration of novel therapeutic approaches is crucial for improving patient outcomes. Transcranial magnetic stimulation (TMS) has emerged as a promising non-invasive neuromodulation technique that may provide benefit in AD management. This review discusses the pathophysiological mechanisms by which TMS operates, evaluates its clinical efficacy in AD patients, assesses its safety profile, and suggests future directions for research.

Fields of Study & Subjects

Transcranial Magnetic Stimulation Studies Dementia and Cognitive Impairment Research Alzheimer's disease research and treatments

Publication details

Journal / source
Life
Volume
16
Issue
3
Pages
397–397
Publication date
28 February 2026
Language
EN