Synthesis of 5′-Chlorospiro(benzo[d][1,3]dioxole-2,4′-[1,2,6]thiadiazin)-3′-amine and 10-Chloro-1,4-dioxa-8-thia-7,9-diazaspiro[4.5]deca-6,9-dien-6-amine

Molbank 2026 Open access

Read full text
Authors: Andreas S. Kalogirou, Panayiotis A. Koutentis
DOI: 10.3390/m2125
Cited by: 0
References: 20

Abstract

Reactions of 3′,5′-dichlorospiro(benzo[d][1,3]dioxole-2,4′-[1,2,6]thiadiazine) or 6,10-dichloro-1,4-dioxa-8-thia-7,9-diazaspiro[4.5]deca-6,9-diene with ammonia in MeCN, at ca. 20 °C, gave 5′-chlorospiro(benzo[d][1,3]dioxole-2,4′-[1,2,6]thiadiazin)-3′-amine and 10-chloro-1,4-dioxa-8-thia-7,9-diazaspiro[4.5]deca-6,9-dien-6-amine, respectively, in near quantitative yields.

Fields of Study & Subjects

Structural and Chemical Analysis of Organic and Inorganic Compounds Synthesis of heterocyclic compounds Chemical synthesis and pharmacological studies

Publication details

Journal / source
Molbank
Volume
2026
Issue
1
Pages
M2125–M2125
Publication date
16 January 2026
Language
EN