(4S*,10aS*,11S*)-4-Hydroxy-2,7,7-trimethyl-11-(4-methylbenzoyl)-7,8-dihydro-10H-4,10a-methano[1,4]oxazino[3,4-d][1,3,5]thiadiazepine-5,10(4H)-dione

Molbank 2026 Open access

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Authors: Nikita A. Tretyakov, Andrey Nikolaevich Maslivets
DOI: 10.3390/m2143
Cited by: 0
References: 15

Abstract

The reaction of 4,4-dimethyl-8-(4-methylbenzoyl)-3,4-dihydro-1H-pyrrolo[2,1-c][1,4]oxazine-1,6,7-trione with thioacetamide in a 1:1 ratio when refluxed in dichloromethane gives (4S*,10aS*,11S*)-4-hydroxy-2,7,7-trimethyl-11-(4-methylbenzoyl)-7,8-dihydro-10H-4,10a-methano[1,4]oxazino[3,4-d][1,3,5]thiadiazepine-5,10(4H)-dione with a good yield. This compound was fully characterized.

Fields of Study & Subjects

Synthesis and pharmacology of benzodiazepine derivatives Structural and Chemical Analysis of Organic and Inorganic Compounds Chemical synthesis and pharmacological studies

Publication details

Journal / source
Molbank
Volume
2026
Issue
2
Pages
M2143–M2143
Publication date
3 March 2026
Language
EN