Synthesis of Ethyl 2-Amino-6-hydroxy-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate and Ethyl 6-(Acetyloxy)-2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate

Molbank 2026 Open access

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Authors: Andrii Yu. Myshastyi, Sergiy V. Vlasov, Hanna Severina, Georgiy G. Yakovenko, Andrii R. Khairulin
DOI: 10.3390/m2144
Cited by: 0
References: 37

Abstract

An effective one-step synthetic procedure for preparation of hydroxylated analogues of ethyl 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate as novel promising multifunctional building blocks for drug discovery based on the Gewald procedure was developed.

Fields of Study & Subjects

Synthesis of heterocyclic compounds Multicomponent Synthesis of Heterocycles Synthesis and Reactivity of Sulfur-Containing Compounds

Publication details

Journal / source
Molbank
Volume
2026
Issue
2
Pages
M2144–M2144
Publication date
4 March 2026
Language
EN