Analysis Methods and Structure–Activity Relationships of Polysaccharides in Sea Cucumber: A Review

Marine Drugs 2026 Open access

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Authors: Xingyu Gu, Pengneng Yu, Yuyang Li, Yuyang Li, Rui Feng, Dong Lv, Zhuoran Song, Tong Geng, Yubo Qin, Ying Li, Ying Li, Zhibo Li
+1 more Qiancheng Zhao
DOI: 10.3390/md24020054
Cited by: 5
References: 126

Abstract

Sea cucumber polysaccharide is a kind of heteropolysaccharide rich in sulfate groups, which has complex structures and various biological activities. Its biological activity is closely related to its chemical composition, molecular weight, and sulfated patterns. Therefore, in order to study the biological activity of sea cucumber polysaccharide, the analysis methods of a sea cucumber polysaccharide structure were comprehensively summarized, and the neutral polysaccharide, fucosylated chondroitin sulfate, and sulfated fucan of sea cucumber were reviewed. The structural characteristics of sea cucumber polysaccharide were expected to provide a theoretical basis for subsequent studies on the biological activity and structure-activity relationship of sea cucumber polysaccharide.

Fields of Study & Subjects

Seaweed-derived Bioactive Compounds Echinoderm biology and ecology Polysaccharides and Plant Cell Walls

Publication details

Journal / source
Marine Drugs
Publisher
MDPI AG
Volume
24
Issue
2
Pages
54–54
Publication date
24 January 2026
Language
EN