Unraveling the Complexities of Small Intestinal Bacterial Overgrowth

Medicina 2026 Open access

Read full text
Authors: Enrico Capuano, Angelo Del Gaudio, Enrico Celestino Nista, Sara Sofia De Lucia, Antonio Pellegrino, Giuseppe Cuccia, Angela Saviano, Carmine Petruzziello, Veronica Ojetti
DOI: 10.3390/medicina62030485
Cited by: 2
References: 145

Abstract

This narrative review explores the intricate dynamics of Small Intestinal Bacterial Overgrowth (SIBO), a condition marked by an excessive growth of bacteria in the small intestine. We delve into the multifaceted etiology of SIBO, including its associations with gastrointestinal disorders, motility issues, and alterations in gut architecture. The review examines current diagnostic methodologies, emphasizing the distinctions between breath testing and direct aspiration techniques. Furthermore, we assess the various treatment approaches, ranging from antibiotics and dietary modifications to emerging therapeutic options. By synthesizing the latest research findings, we aim to enhance understanding of SIBO's implications for gut health and provide insights into effective management strategies.

Fields of Study & Subjects

Gastrointestinal motility and disorders Gut microbiota and health Intestinal Malrotation and Obstruction Disorders

Publication details

Journal / source
Medicina
Publisher
MDPI AG
Volume
62
Issue
3
Pages
485–485
Publication date
4 March 2026
Language
EN