Respiratory and Pleural Pathogens in Octogenarians Hospitalized with COVID-19: Impact of Secondary Bacterial Pneumonia on Day-5 SOFA and Mortality
Abstract
Background and Objectives: Secondary bacterial infection drives poor outcomes in older adults with COVID-19, but age-specific microbiology and its interaction with severity scores are not well defined. We characterized respiratory and pleural pathogens, resistance profiles, and their impact on day-5 SOFA/APACHE II in octogenarians versus younger adults. Methods: We performed a retrospective cohort study of adults with RT-PCR-confirmed coronavirus disease 2019 (COVID-19) at a tertiary infectious diseases center (≥80 years, n = 152;
Fields of Study & Subjects
COVID-19 Clinical Research Studies
Pneumonia and Respiratory Infections
Nosocomial Infections in ICU
Publication details
- Journal / source
- Microorganisms
- Volume
- 14
- Issue
- 1
- Pages
- 164–164
- Publication date
- 12 January 2026
- Language
- EN