Drimane Sesquiterpenes Isolated from the Fruiting Body of the Clavarioid Fungus Ramaria botrytoides
Abstract
Four previously undescribed drimane-type sesquiterpenoids, ramaribotrytols A–D (1–4), were isolated from the fruiting bodies of the clavarioid fungus Ramaria botrytoides. Their structures and absolute configurations were elucidated by comprehensive 1D and 2D NMR spectroscopic analyses, high-resolution electrospray ionization mass spectrometry (HRESIMS), and electronic circular dichroism (ECD) calculations. Compounds 1–4 are characterized by oxygenation at C-2, a structural feature that is rare within the drimane sesquiterpene family. These findings expand the chemical diversity of secondary metabolites from the medicinal and edible fungus Ramaria and enrich the structural repertoire of drimane-type sesquiterpenoids derived from higher fungi.
Fields of Study & Subjects
Marine Sponges and Natural Products
Microbial Natural Products and Biosynthesis
Diatoms and Algae Research
Publication details
- Journal / source
- Molecules
- Publisher
- MDPI AG
- Volume
- 31
- Issue
- 4
- Pages
- 645–645
- Publication date
- 13 February 2026
- Language
- EN