Growth Recovery After Fetal Growth Restriction: A 10-Year Follow-Up of Term-Born Children

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Authors: Anca Adam-Raileanu, Alin Horatiu Nedelcu, Ancuța Lupu, Viorel Ţarcă, Laura Iulia Bozomitu, Lorenza Forna, Ileana Ioniuc, Cristina Maria Mihai, Tatiana Chisnoiu, Elena Țarcă, Ionela Daniela Morariu, Emil Anton
+2 more Bogdan Puha, Vasile Valeriu Lupu
Cited by: 2
References: 60

Abstract

Background/Objectives: Fetal growth restriction (FGR) describes the situation of a fetus that fails to reach its genetic growth potential. Postnatal catch-up growth represents a central adaptive process, yet its timing and magnitude vary widely and may influence one individual’s state of health and later metabolic risk. This study aimed to characterize longitudinal growth trajectories from birth to 10 years in children born at term, affected antenatally by growth restriction, with a particular focus on the influence of sex and FGR severity on catch-up growth. Methods: We conducted a retrospective observational study including 170 term-born children with documented FGR, admitted to a tertiary pediatric center between 2019 and 2023. Anthropometric data (weight, length/height, BMI) at birth, 1, 2, 5, and 10 years were converted to World Health Organization (WHO) age- and sex-adjusted z-scores. Catch-up growth was defined as an increase of >0.67 SD. Participants were stratified by sex and FGR severity (moderate: 10th–3rd percentile; severe:

Fields of Study & Subjects

Birth Development and Health Pregnancy and preeclampsia studies Gestational Diabetes Research and Management

Publication details

Journal / source
Nutrients
Publisher
MDPI AG
Volume
18
Issue
2
Pages
243–243
Publication date
13 January 2026
Language
EN