Growth Recovery After Fetal Growth Restriction: A 10-Year Follow-Up of Term-Born Children
Abstract
Background/Objectives: Fetal growth restriction (FGR) describes the situation of a fetus that fails to reach its genetic growth potential. Postnatal catch-up growth represents a central adaptive process, yet its timing and magnitude vary widely and may influence one individual’s state of health and later metabolic risk. This study aimed to characterize longitudinal growth trajectories from birth to 10 years in children born at term, affected antenatally by growth restriction, with a particular focus on the influence of sex and FGR severity on catch-up growth. Methods: We conducted a retrospective observational study including 170 term-born children with documented FGR, admitted to a tertiary pediatric center between 2019 and 2023. Anthropometric data (weight, length/height, BMI) at birth, 1, 2, 5, and 10 years were converted to World Health Organization (WHO) age- and sex-adjusted z-scores. Catch-up growth was defined as an increase of >0.67 SD. Participants were stratified by sex and FGR severity (moderate: 10th–3rd percentile; severe:
Fields of Study & Subjects
Birth
Development
and Health
Pregnancy and preeclampsia studies
Gestational Diabetes Research and Management
Publication details
- Journal / source
- Nutrients
- Publisher
- MDPI AG
- Volume
- 18
- Issue
- 2
- Pages
- 243–243
- Publication date
- 13 January 2026
- Language
- EN