Fermented Noni Polysaccharides and Immune-Related Biomarkers in Adults with Recurrent URTIs: A Randomized, Double-Blind, Placebo-Controlled Trial

Nutrients 2026 Open access

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Authors: Seon-mi Shin, Seong-Hwan Park, Seon-Gyu Bae, Eun-Young Park, Jae-Yeon Lee, Hee‐Yeon Kwon, Im-Joung La, Sang-Jun Youn, Young Sik Choi, Yeong-eun Choi, 김도희, Sun‐Young Park
+2 more Cheol Moon, Tae-Yeon Kim
DOI: 10.3390/nu18111691
Cited by: 1
References: 28

Abstract

Background: Fermented polysaccharides derived from Morinda citrifolia (noni) have been suggested to modulate innate immune responses, but clinical evidence remains limited. Objectives: This randomized, double-blind, placebo-controlled trial evaluated the effects of fermented noni polysaccharides on natural killer (NK) cell activity and immune-related biomarkers in adults with recurrent upper respiratory tract infections (URTIs). Methods: A total of 100 adults aged 40 to

Fields of Study & Subjects

Morinda citrifolia extract uses Herbal Medicine Research Studies Papaya Research and Applications

Publication details

Journal / source
Nutrients
Publisher
MDPI AG
Volume
18
Issue
11
Pages
1691–1691
Publication date
26 May 2026
Language
EN