Stratified Therapeutic Drug Monitoring Could Potentially Improve the Efficacy and Safety of Oxcarbazepine in Children with Epilepsy: Novel Insights from a Single-Center, Large-Sample, Retrospective Real-World Study

Pharmaceuticals 2026 Open access

Read full text
Authors: Yi-Jing Liu, Xi-Li Sun, Yue Li, Xiao-peng Lu, Chun-Feng Wu, Hu Guo, Feng Chen
DOI: 10.3390/ph19030415
Cited by: 0
References: 52

Abstract

Objective: This study aimed to characterize the population exposure, efficacy, and safety profiles of oxcarbazepine (OXC) in Chinese children with epilepsy using real-world data, define its optimal therapeutic range, and inform individualized therapy. Methods: This single-center retrospective cohort study included pediatric patients (

Fields of Study & Subjects

Epilepsy research and treatment Pharmacological Effects and Toxicity Studies Pharmaceutical studies and practices

Publication details

Journal / source
Pharmaceuticals
Volume
19
Issue
3
Pages
415–415
Publication date
3 March 2026
Language
EN