Growth Retardation in an Adolescent Secondary to Cushing’s Disease Caused by a Pituitary Microadenoma: A Case Report

Introduction and Clinical Significance: Cushing’s disease is a rare but clinically consequential cause of endogenous hypercortisolism in children, most commonly resulting from ACTH-secreting pituitary microadenomas. In contrast to adults, growth deceleration accompanied by disproportionate weight gain represents the earliest and most sensitive clinical marker in pediatric cases. Sustained hypercortisolism during critical periods of somatic maturation may compromise final height, disrupt pubertal progression, and induce persistent metabolic and neurocognitive sequelae, even after biochemical remission. Early recognition and timely intervention are, therefore, essential to preserve developmental trajectories. Case Presentation: A 13-year-and-8-month-old boy was referred for evaluation of progressive linear growth impairment, markedly reduced growth velocity (0.8 cm/year;