Plasma Exchange in the Setting of Acute Ibuprofen Poisoning: A Case and Review of the Literature
Abstract
Background and Clinical Significance: Extracorporeal therapies such as hemodialysis, continuous renal replacement therapy (CRRT) or therapeutic plasma exchange (TPE) are mainstay treatments for acute toxins, venoms and poisonings. Ibuprofen is a common drug implicated in acute toxicity, with a major complication being acute kidney injury (AKI). As such, these patients often receive hemodialysis or CRRT, which do not remove substances with high protein binding (>80%) and low volumes of distribution (Vd) (
Fields of Study & Subjects
Poisoning and overdose treatments
Drug-Induced Hepatotoxicity and Protection
Acute Kidney Injury Research
Publication details
- Journal / source
- Reports — Medical Cases Images and Videos
- Publisher
- MDPI AG
- Volume
- 9
- Issue
- 3
- Pages
- 228–228
- Publication date
- 16 July 2026
- Language
- EN