Retained Amniochorionic Tissue Managed with Office Hysteroscopy Using a 16 Fr Bipolar Mini-Resectoscope Under Nitrous Oxide Analgesia: A Case Report of “Positive Hysteroscopy”

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Authors: Alessandro Messina, Alessandro Libretti, Daniele De Ruvo, Paolo Alessi, Giovanni Lipari, Tiziana Bruno, Daniela Caronia, Sofia Vegro, Livio Leo, Bianca Masturzo
Cited by: 0
References: 20

Abstract

Background: Retained products of conception (RPOC) after term delivery are uncommon but may lead to persistent abnormal uterine bleeding and other complications. Hysteroscopic removal is considered the optimal management strategy, and technological advances have increasingly enabled operative procedures to be performed safely in an office setting. Clinical case: We report the case of a 43-year-old woman who presented with intermittent spotting four months after spontaneous vaginal delivery. Transvaginal ultrasound revealed a small, avascular hyperechoic intrauterine lesion consistent with retained amniochorionic tissue. She underwent office hysteroscopic removal using a 16 Fr bipolar mini-resectoscope under nitrous oxide (N2O) buccal–nasal analgesia. The procedure was performed using a vaginoscopic, no-touch approach without speculum, tenaculum, or cervical dilation. Complete resection was achieved in a seven-minute procedure, with a postoperative pain score of 2/10 on the VAS and no complications. At 30-day follow-up, the patient was asymptomatic, and an ultrasound confirmed complete resolution. Conclusion: This case demonstrates that retained amniochorionic tissue can be safely and effectively treated in a fully ambulatory setting using mini-resectoscopic technology and N2O analgesia. The combination of minimally invasive instruments, patient-centered procedural strategies, and well-tolerated analgesia supports the growing role of office operative hysteroscopy for selected complex intrauterine conditions.

Fields of Study & Subjects

Gynecological conditions and treatments Maternal and Perinatal Health Interventions Maternal and fetal healthcare

Publication details

Journal / source
Reproductive Medicine
Volume
7
Issue
1
Pages
3–3
Publication date
5 January 2026
Language
EN