Stability and Forward Bifurcation Analysis of an SIPIVR Model for Poliovirus Transmission with Neural Network
Abstract
The aim of this research is to formulate and analyze a modified SIpIVR mathematical model to study the transmission dynamics of poliovirus and assess the impact of vaccination on disease control. The proposed model extends classical SEIV-type frameworks by incorporating a recovered compartment with long-term immunity and by replacing the traditional exposed class with a pre-infectious compartment (Ip) that captures silent viral shedding during the incubation phase of poliovirus. This modification addresses the critical epidemiological feature that individuals can transmit the virus before showing symptoms while maintaining biological accuracy in compartment definition. Several fundamental analytical properties are rigorously established, including positivity, boundedness, and the existence of a biologically meaningful invariant region. The basic reproduction number R0 is derived using the next-generation matrix approach, and comprehensive stability analysis is carried out. The analysis shows that the DFE is locally and globally asymptotically stable whenever R0
Fields of Study & Subjects
Viral Infections and Immunology Research
Mathematical and Theoretical Epidemiology and Ecology Models
COVID-19 epidemiological studies
Publication details
- Journal / source
- Symmetry
- Publisher
- MDPI AG
- Volume
- 18
- Issue
- 3
- Pages
- 435–435
- Publication date
- 2 March 2026
- Language
- EN