Impact of Early Versus Late Treatment with Botulinum Toxin A on Goal Attainment in Post-Stroke Spasticity: A Retrospective Cohort Study

Toxins 2026 Open access

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Authors: Atul Patel, Jinming Zhang, Simon Page, Sarah Harding, Mathieu Beneteau, Colin Navickas, Alberto Esquenazi
DOI: 10.3390/toxins18020068
Cited by: 1
References: 28

Abstract

This study evaluated the effect of time of botulinum toxin A (BoNT-A) treatment on clinical outcomes in adults with post-stroke spasticity (PSS). Individual data were pooled from five studies. Eligible patients received ≥1 BoNT-A injection(s) for PSS and had goal attainment scaling (GAS) scores measured at baseline and 12 weeks. Patients were grouped according to time of treatment post-stroke: early (

Fields of Study & Subjects

Botulinum Toxin and Related Neurological Disorders Stroke Rehabilitation and Recovery Cerebral Palsy and Movement Disorders

Publication details

Journal / source
Toxins
Publisher
MDPI AG
Volume
18
Issue
2
Pages
68–68
Publication date
27 January 2026
Language
EN