Factors associated with quality of life in patients with heart failure and its impact on mortality

BACKGROUND: In heart failure (HF), patients' quality of life (QoL) is influenced not only by cardiacfunction but also by coexisting conditions. Despite the widespread use of QoL assessments, therole of patient-related factors as determinants of QoL remains not fully elucidated. AIMS: This study aims to assess the relative impact of different factors on QoL in HF patients, as well as its impact on mortality in this group. METHODS: The study was based on the national registry - HEart failuRe ObsErvational Study of the Polish Cardiac Society, in which QoL was assessed at baseline (Kansas City CardiomyopathyQuestionnaire [KCCQ]-12), and follow-up data on all-cause mortality were obtained. Adjusted linearregression was used to identify factors associated with KCCQ-12. RESULTS: The study included 1397 patients with a median KCCQ-12 score of 47.92 (28.65-72.92). Higher New York Heart Association class patients had consistently lower values of all KCCQ-12domains and KCCQ-12 overall scores (85 [69-93] vs. 65 [46-79] vs. 35 [23-49] vs. 21 [10-38]; allP