Gadolinium mono and bisphthalocyanine obtained in a single synthesis and their bactericidal activity

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Authors: Cassia Jackline Tavares, Adonilson R. Freitas, Milena Noronha dos Santos, Helton José Wiggers, Luciana Gaffo
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Abstract

Phthalocyanines can be prepared in different forms. The synthesis using lanthanides metals, in general, results in bisphthalocyanines molecules, while synthesis with transitions metals can produce monophthalocyanine, simple called phthalocyanines. To obtain one or another form of the compounds it is necessary to carry out more than one synthesis, using small differences in the temperature. In this paper we reported, for the first time, a synthesis where could be obtained a compound containing both forms of gadolinium, mono (GdPc) and bisphthalocyanine (GdPc2). Different forms were separated and characterized by spectroscopy methods (absorption and infrared). The obtained forms were tested for antibacterial activities using the Pseudomonas aeruginosa in agar diffusion method and broth dilution assays, showed that only GdPc2 presented activity aganst this bacteria.

Fields of Study & Subjects

Porphyrin and Phthalocyanine Chemistry Photodynamic Therapy Research Studies Metal complexes synthesis and properties

Publication details

Journal / source
Brazilian Journal of Development
Volume
12
Issue
2
Pages
e85450–e85450
Publication date
2 February 2026