The Impact of Antiparasitic Therapy on the Dynamics of Inflammatory Periodontal Diseases in Patients with Chronic Intestinal Parasitoses

Introduction: Chronic inflammatory periodontal diseases remain one of the most significant challenges in modern dentistry, affecting a substantial portion of the adult population worldwide. According to systematic reviews, the prevalence of moderate periodontitis reaches 45-50%, while severe forms affect 11-15% of the population, ranking this pathology as the sixth most prevalent condition globally. Methods: A prospective cohort study was conducted to evaluate the effect of antiparasitic therapy on the periodontal status of 80 patients with chronic intestinal parasitoses. The study group comprised 40 patients with verified giardiasis or enterobiasis, while the control group consisted of 40 patients without parasitic infections. Assessments were performed before treatment and at 1, 3, and 6 months post-therapy. Standard periodontal indices (PBI, OHI-S, CPI) and laboratory methods (CRP, ferritin, vitamin B12, eosinophils) were employed. Results: The results demonstrated that patients with intestinal parasitoses initially exhibited statistically significant higher markers of periodontal inflammation: PBI index 3.8±0.4 points versus 2.1±0.3 points in controls (P