Evaluación de la adherencia a psicofármacos: Estudio farmacoepidemiológico de registro en Castilla y León.

INTRODUCTION: The use of antidepressants and anti-dementia drugs has increased in recent years. Patients with depression, anxiety, or dementia are more likely to not adhere to treatment. Non-adherence is associated with poorer health outcomes and increased morbidity and mortality. Additionally, nonadherence correlates with a considerable increase in healthcare costs. OBJECTIVES: 1) Evaluate non-adherence to antidepressants and anti-dementia drugs and analyze predisposing factors. 2) Evaluate the economic impact of nonadherence to antidepressants. METHODS: This was a population-based epidemiological registry study. Pharmaceutical consumption data was obtained from the pharmaceutical service information system in Castilla y León (CONCYLIA). An indirect method based on the medication possession ratio (MPR) was used to estimate adherence. Patients with an MPR