Application of Spider Silk-Based Materials in Regenerative Medicine: From In Vivo Studies to Clinical Use

Innovative medicine of Kuban 2026 Open access

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Authors: R. A. Zamanova, Svetlana Piatnitskaia, A. I. Fairushina, Ш. М. Сафин, Vladimir A. Smirnov, Michael Lebenstein-Gumovski, E. D. Grigorevskiy, A. A. Grin, V. V. Krylov, V. N. Pavlov
DOI: 10.35401/2541-9897-2026-11-1-123-131
Cited by: 0
References: 33

Abstract

This review examines the use of spider-silk-based materials in regenerative medicine. Spider silk possesses a unique combination of mechanical and biological properties, making it a promising biomaterial for tissue engineering. An analysis of in vivo studies in animal models and the first clinical trials is presented, demonstrating the ability of spider silk to direct cell growth, accelerate wound healing, and promote peripheral nerve regeneration. The prospects for large-scale production of spider silk and its medical applications are discussed.

Fields of Study & Subjects

Silk-based biomaterials and applications Electrospun Nanofibers in Biomedical Applications Bone Tissue Engineering Materials

Publication details

Journal / source
Innovative medicine of Kuban
Volume
11
Issue
1
Pages
123–131
Publication date
1 March 2026
Language
EN