A review of the application potential of hyperoside in the regulation of glycolipid metabolism in livestock and poultry

Abnormalities in glycolipid metabolism are important health problems faced in livestock and poultry farming, which can lead to growth retardation, decreased production performance and multi-organ complications.Hyperoside (HYP) is a natural flavonoid compound found in various plants such as Forsythia pinnata, Forsythia suspensa, and Cuscuta chinensis.Medical studies have revealed that HYP exhibits a wide range of biological activities, including anticancer, anti-inflammatory, antibacterial, antiviral, antidepressant, and organ-protective effects.It is worth noting that HYP has demonstrated the intervention potential of multi-target and multi-pathway in the regulation of glycolipid metabolism.This paper systematically reviews its effects on glycolipid metabolism and related core molecular mechanisms by regulating carbohydrate absorption, improving insulin sensitivity, and protecting target organs such as the kidneys and liver.Additionally, this paper explores the potential of fibronectin type III domain-containing protein 5 (FNDC5) as a target for HYP to regulate glycolipid metabolism and thus influence meat quality, providing a theoretical basis for its development as a green feed additive and application in the livestock industry.