Importancia de la frecuencia de las manifestaciones clínicas como la hiperreflexia en el síndrome de Guillain Barré. Informe de caso atípico

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Authors: Miguel Jacob Ochoa-Andrade, Wilian J. López-Franco, Margarita Monserrate Santana-López, Carlos Alejandro Fajardo-Vargas
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Abstract

INTRODUCTION. Guillain-Barré syndrome is an acute inflammatory autoimmune neuritis whose most common type is acute inflammatory demyelinating polyneuropathy, with a mean age of onset of 40 years, with a predominance in men of all ages, races and nationalities. It is characterized by symmetrical ascending muscle weakness predominantly distal, generating a decrease or absence of deep tendon reflexes and which can compromise the cranial nerves, especially the seventh. CLINICAL CASE. A 23-year-old mixed-race male patient with a diagnosis of Guillain Barré who presented hyperreflexia in the lower extremities, without albumin-cytological dissociation. DISCUSSION. The phenomenon of hyperreflexia has been described in 13% of cases with Guillain Barré Syndrome, and the majority of cases occur in patients with acute motor axonal form. When reviewing the literature, cases of hyperreflexia commonly present as a late phenomenon towards the second week of evolution. Albumino-cytological dissociation can occur in approximately 35% of cases. CONCLUSIONS. It is important to report variations in the usual clinical manifestations of Guillain Barré in order to establish the diagnosis quickly and initiate treatment early and thus reduce possible sequelae.

Fields of Study & Subjects

Peripheral Neuropathies and Disorders Peripheral Nerve Disorders Hereditary Neurological Disorders

Publication details

Publication date
3 February 2026
Language
ES
Document type
Dataset