Laryngeal Cancer in Women: Experience of the Radiation Oncology Department of Marrakech

Introduction: Laryngeal cancer is rare in women and is frequently diagnosed at an advanced stage. Data specifically addressing this population remain limited. Objective: The objective of this study was to describe the epidemiological, clinical, histopathological, therapeutic, and outcome characteristics of laryngeal cancer in women treated at the Department of Radiation Oncology of CHU Mohammed VI of Marrakech. Materials and Methods: This retrospective descriptive study included 12 female patients treated for histologically confirmed laryngeal cancer between January 2019 and December 2024. Clinical, paraclinical, therapeutic, and outcome data were analyzed. Tumor staging was performed according to the AJCC/UICC 8th edition TNM classification. Results: The mean age was 63 years. Dysphonia was the main presenting symptom. Locally advanced stages (III–IVA) accounted for 83% of cases. Surgery was performed in six patients, and radiotherapy was administered in all patients using different modalities. Overall treatment tolerance was satisfactory. The best outcomes were observed in patients treated at an early stage and in those who underwent surgery followed by radiotherapy. Conclusion: Laryngeal cancer in women is often diagnosed at an advanced stage. Multidisciplinary management allows satisfactory locoregional disease control.