Secretory Adrenal Adenoma in Children: A Case Report

Secretory adrenal adenoma is an uncommon cause of endocrine disturbance in the pediatric population, often presenting with clinical features of hormone excess. This case report describes a 9-year-old girl who presented with a two-year history of progressive virilization, including hirsutism, pubic hair development, obesity, and severe acne. Laboratory evaluation confirmed hyperandrogenism, and computed tomography revealed a 45-mm right adrenal mass. The patient underwent right adrenalectomy, and histopathological examination confirmed a benign adrenal adenoma. Postoperative follow-up demonstrated significant clinical, biological, and psychological improvement with regression of Cushingoid features. This case highlights the diagnostic challenges of pediatric adrenal tumors and underscores the importance of surgical management and long-term monitoring, given the uncertain boundary between benign and malignant adrenal cortical lesions in children.